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التصنيف: psychiatric.antidepressants
المادة الفعالة: bupropion

about bupropion norepinephrine and dopamine reuptake inhibitor nicotinic antagonist aminoketone derivative atypical antidepressant smoking cessation aid. mechanism of action of bupropion bupropion blocks the re-uptake of neurotransmitter dopamine and noradrenaline from the synapse in to the presynaptic nerve terminal in the cns. it has only a less activity in blocking the reuptake of serotonin. bupropion potentiates the noradrenergic and dopaminergic activity and produces antidepressant activity. smoking cessation action: bupropion is a competitive antagonist of nicotine. indications for bupropion 1. depression 2. smoking cessation treatment